Pick-up sticks or pick-a-stick is a game of physical and mental skill. A bundle of 'sticks', between 8 and 20 centimeters long, are held in a loose bunch and released on a table top, falling in random disarray. Each player, in turn, must remove a stick from the pile without disturbing the remaining ones. One root of the name "pick-up sticks" may be the line of a children's nursery rhyme, "...five, six, pick-up sticks!" The game has spawned several variations such as Jackstraws (or Jack Straws), Spellicans, and Spillikins.

The sticks can be made out of ivory, bone, wood, bamboo, straw, reed, rush, yarrow, or plastics.